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Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. 

Uses Of Sibutramine:

• Psychiatric conditions as bulimia nervosa, anorexia nervosa, serious depression or pre-existing mania
• Patients with a history of or a predisposition to drug or alcohol abuse
• Hypersensitivity to the drug or any of the inactive ingredients
• Patients below 18 and above 65 years of age
• Concomitant treatment with an MAO inhibitor, antidepressant or other centrally active drugs, particularly other anoretics
• History of peripheral arterial disease
• Hypertension that is not sufficiently controlled (e.g., >145/90 mmHg), caution in controlled hypertension
• Existing pulmonary hypertension
• Existing damage on heart valves, coronary heart disease, congestive heart failure, serious arrhythmias, previous myocardial infarction
• A history of coronary artery disease (e.g., angina, history of myocardial infarction), congestive heart failure, tachycardia, peripheral arterial
• occlusive disease, arrhythmia or cerebrovascular disease (stroke or transient ischemic attack (TIA))
• Stroke or transient ischemic attack (TIA)
• Hyperthyroidism (overactive thyroid gland)
• Closed-angle glaucoma
• Seizure disorders
• Enlargement of the prostate gland with urinary retention (relative contraindication)
• Pheochromocytoma
• Pregnant and lactating women (relative contraindication). online.

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